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Monday, July 9, 2018

She Has Her Mother's Laugh by Carl Zimmer



Review of:

She Has Her Mother's Laugh: The Powers, Perversions, and Potential of Heredity


by
Carl Zimmer (Goodreads Author)



Carl Zimmer presents a history of our understanding of heredity in this sweeping, resonating overview of a force that shaped human society--a force set to shape our future even more radically.

She Has Her Mother's Laugh presents a profoundly original perspective on what we pass along from generation to generation. Charles Darwin played a crucial part in turning heredity into a scientific question, and yet he failed spectacularly to answer it. The birth of genetics in the early 1900s seemed to do precisely that. Gradually, people translated their old notions about heredity into a language of genes. As the technology for studying genes became cheaper, millions of people ordered genetic tests to link themselves to missing parents, to distant ancestors, to ethnic identities. . . .

But, Zimmer writes, "Each of us carries an amalgam of fragments of DNA, stitched together from some of our many ancestors. Each piece has its own ancestry, traveling a different path back through human history. A particular fragment may sometimes be cause for worry, but most of our DNA influences who we are--our appearance, our height, our penchants--in inconceivably subtle ways." Heredity isn't just about genes that pass from parent to child. Heredity continues within our own bodies, as a single cell gives rise to trillions of cells that make up our bodies. We say we inherit genes from our ancestors--using a word that once referred to kingdoms and estates--but we inherit other things that matter as much or more to our lives, from microbes to technologies we use to make life more comfortable. We need a new definition of what heredity is and, through Carl Zimmer's lucid exposition and storytelling, this resounding tour de force delivers it.

Weaving historical and current scientific research, his own experience with his two daughters, and the kind of original reporting expected of one of the world's best science journalists, Zimmer ultimately unpacks urgent bioethical quandaries arising from new biomedical technologies, but also long-standing presumptions about who we really are and what we can pass on to future generations.
 



Leona's Review:



This was a very interesting read. It is a long book, 574 pages, but an easy read for the average person. For those interested in genealogy research, I think this is a must read.
I received a complimentary copy from goodreads.com to read. The opinions are my own. I give this book a 5 stat rating. I gave my copy to a granddaughter who is in the medical field for neurology.




I am a note taker and so I will what add some I thought are interesting and helpful suggestions for the reader.

PKU  Phenylketonuria is an inherited disorder that can lead to developmental delay, behavior  problems and seizures. page 471
Margaret Mead  page 461 
Homo Sapiens page 467
Homo Erectus page 467
Neandertals page 467
Denisovans page 467
Cumulative culture page 463
Mitochondrial replacement page 517
Human altered environment page 466
Agriculture Revolution page 469
Fetal alcohol page 479
Human germ line engineering page 524
Gene therapy  page 509 replacement
Cloned frog before Dolly  page 544
Arygan race page 498
Blood disorders page 509
3 Parent children  page 514 ooplasm
Macular degeneration  page 277
Twins page 297
Omnigenic page 304
Power of the human brain 
Twins
"Failure is common in science"  page 552
Mendel's Law 
Mosaics page 350
Mosaic neurons page 369
Memories store in brain page 431
Thyroid page 390
Research in epigenetics page 436
Burbank potatoes Russet potatoes page 444 
Growth plates
Maryland Iron Mines in 1700s
Scotland study
Captain Cook page 467
Nootka Vancouver Island

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